Active Ingredient	Liposomal Amphotericin B
Manufacturer	Gilead
Origin	Turkey
Reference	N/A

What is Ambisome (Liposomal Amphotericin B) used for?

AmBisome (Liposomal Amphotericin B) is used in the treatment of various different fungal infections. Uses include systemic fungal infections (Aspergillus species, Candida species, and/or Cryptococcus species) Cryptococcal meningitis and Visceral Leishmaniasis. AmBisome is classified as an antifungal antibiotic. It prevents the further spread of infection by killing the fungus.

How should I use Ambisome (Liposomal Amphotericin B)?

AmBisome is comes in a powder form that needs to be reconstituted before use. The solution will then be administered by an intravenous drip. Only use the dosage specified by your doctor for your condition.

What are the side effects of Ambisome (Liposomal Amphotericin B)?

Common side effects associated with Ambisome include:

• Hypokalemia
• Hypomagnesemia
• Chills
• Anemia
• Nephrotoxicity
• Nausea
• Vomiting
• Diarrhea
• Rash
• Dyspnea
• Hyperglycemia
• Insomnia
• Alkaline phosphatase increase
• Infusion reaction
• Headache
• Hypertension
• Abdominal pain
• Tachycardia
• Lung disorder
• Blood transfusion reaction
• Hypocalcemia
• Cough
• Bilirubinemia
• Leukopenia
• ALT increased
• Constipation
• Peripheral edema
• Pain
• Anorexia
• Anxiety
• Hypotension
• Sepsis
• AST increased
• Pleural effusion
• Confusion
• Thrombocytopenia
• Weakness
• Back pain
• Edema
• Hyponatremia
• Chest pain
• Hypervolemia
• Pruritus
• Rhinitis
• Phlebitis

Less common side effects you may notice when taking AmBisome include:

• Abnormal thinking
• Acidosis
• Agitation
• Alopecia
• Arthralgia
• Asthma
• Bruising
• Cardiovascular abnormalities
• Coagulation disorder
• Cellulitis
• Depression
• Dizziness
• Electrolyte abnormalities
• Fluid overload
• Gastrointestinal hemorrhage
• Hallucinations
• Hyperventilation
• Injection site reaction
• Malaise
• Mucositis
• Petechia
• Rash
• Renal function abnormalities
• Respiratory acidosis
• Respiratory failure
• Seizure
• Stomatitis

Please Note

AmBisome may not be not be your best choice of treatment if you have have had kidney problems.

AmBisome can interact with azole antifungals (ketoconazole, itraconazole, fluconazole, etc.)