What is Aravon (Edaravone) used for?

Aravon (Edaravone) is used to treat amyotrophic lateral sclerosis (ALS) also know as Lou Gehrig's disease or motor neuron disease (MND). This is a condition in which the nerves that control muscle movement slowly die, causing the muscles to shrink and weaken). Edaravone injection is in a class of medications called antioxidants. It may work to slow the nerve damage associated with the worsening of ALS symptoms. Aravon (Edaravone) protects nerve cells by mopping up free radicals in the body.

How should I use Aravon (Edaravone)?

Aravon (Edaravone) is a solution containing 1.5mg/mL. It is to be injected intravenously over 60 minutes. Usually this will need to be performed by a health care professional in a doctor's office or medical facility. It is usually administered once daily for the first 14 days of a 28-day cycle. After the first cycle, it is given once a day for the first 10 days of a 28-day cycle. Your doctor will decide how often you are to receive edaravone based on your body's response.

What are the side effects of Aravon (Edaravone)?

Edaravone can cause serious reactions during or after you receive your infusion. Your doctor may need to stop your treatment if you experience certain side effects. Tell your doctor if you experience any of the following symptoms: wheezing or difficulty breathing, shortness of breath, cough, fainting, flushing, itching, rash, hives, swelling of the throat, tongue, or face, throat tightness, or difficulty swallowing. It is important for you to tell your doctor how you are feeling during your treatment with Aravon (Edavarone). Call your doctor right away or get immediate emergency medical attention if you experience any of these symptoms after you leave your doctor's office or medical facility.

Edaravone injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• bruising
• difficulty walking
• headache
• red, itchy, or scaly rash

Some side effects can be serious. If you experience any of these symptoms or those in the HOW section, call your doctor immediately or get emergency medical treatment:

• difficulty breathing
• chest tightness
• wheezing
• coughing (especially in people with asthma)

Please Note

Before receiving Aravon (Edavarone):

• tell your doctor and pharmacist if you are allergic to edaravone, any other medications, sodium bisulfite, or any of the ingredients in Aravon (Edavarone). Ask your pharmacist for a list of the ingredients.
• tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements, you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
• tell your doctor if you have or have ever had asthma.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while receiving edaravone, call your doctor.