What is Pentasa (Mesalazine) used for?

Pentasa (Mesalazine) is an oral anti-inflammatory drug prescribed to treat ulcerative colitis. It operates by blocking the actions of an enzyme in the body that causes the swelling, pain, and irritation associated with this condition. Your physician may also prescribe it to treat other unlisted conditions.

How should I use Pentasa (Mesalazine)?

Follow your physician's instructions while using Pentasa (Mesalazine) to get the most effective results from treatment. One tablet is normally taken four times daily, but your individual instructions will be based on your health condition and the severity of your symptoms. The tablets should be swallowed whole with a large glass of water and may be taken on an empty stomach. Do not change the form of the tablets by splitting or crushing them to avoid unintentionally destroying or altering the effects of their contents. Ask your pharmacist or physician any questions you have about the medicine to ensure the correct administration.

What are the side effects of Pentasa (Mesalazine)?

Side effects associated with the use of Pentasa (Mesalazine) include:

• Headache
• Dizziness
• Fatigue or drowsiness
• Upset stomach, gassiness, or bloating
• Diarrhea or constipation
• Joint pain
• Flu symptoms (Runny nose, coughing, or sore throat)

More serious side effects that may require medical assistance are intense stomach pain, severe headaches, chest pain, trouble breathing, urinary retention, swelling, unusual weight gain, coughing up blood or a substance resembling coffee grounds, or discolored stools. Inform your physician about any unusual symptoms that worry you to make sure the correct alterations are made to your regimen such as lower doses or reduced frequency of administration.

Please Note

Do not use Pentasa (Mesalazine) if you are allergic to salicylates, if the patient being treated is under the age of fifteen, or if you have blood disorders, severely decreased kidney function, or severely decreased liver function. You should also inform your physician if you are elderly or if you have asthma, allergies to sulfasalazine, decreased liver function, or decreased kidney function. These conditions may cause unexpected problems requiring reduced dosages or other changes to your regimen.

Strictly follow all instructions provided to you by your physician or pharmacist while using Pentasa (Mesalazine). Optimum and safe dosage can differ based on the patient and the condition being treated.

As this medication may be unsafe for certain patients, it is essential you always inform your physician if you are pregnant or breastfeeding, as well as if you have any allergies, other illnesses, or ongoing health conditions, and if you are taking any other form of medication, supplements, or herbal products.

Immediately seek emergency medical care if you have an allergic or hypersensitive reaction. Common signs of a reaction include hives, swelling, skin rashes, chest pains, as well as trouble breathing or swallowing.